Orihel T C, Moore P J
Am J Trop Med Hyg. 1975 Jul;24(4):606-9. doi: 10.4269/ajtmh.1975.24.606.
Four species of primates, baboon (Papio anubis), patas monkeys (Erythrocebus patas), green monkey (Cercopithecus aethiops) and chimpanzee (Pan troglodytes) were inoculated with third-stage larvae of a human strain of Loa loa from Cameroon, West African. The baboon and patas monkeys developed patent infections after 135 to 148 days; the green monkeys and chimpanzee did not. In each animal which became patent, microfilaremia rose rapidly to high levels. In the baboon, but not in the patas monkeys, there was a suppression of microfilaremia during the 4th month of patency. After splenectomy, microfilariae reappeared in the peripheral blood in large numbers. In both baboon and patas monkeys, the microfilariae of Loa loa maintain the diurnal periodicity so characteristic of their behavior in man.
四种灵长类动物，即狒狒（东非狒狒）、赤猴（赤猴）、绿猴（非洲绿猴）和黑猩猩（黑猩猩）接种了来自西非喀麦隆的人源罗阿丝虫第三期幼虫。狒狒和赤猴在135至148天后出现显性感染；绿猴和黑猩猩未出现。在每只出现显性感染的动物中，微丝蚴血症迅速上升至高水平。在狒狒而非赤猴中，在显性感染的第4个月微丝蚴血症受到抑制。脾切除术后，外周血中大量重新出现微丝蚴。在狒狒和赤猴中，罗阿丝虫的微丝蚴都保持着在人体中行为所特有的昼夜周期性。
