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裂殖酵母中的一个线粒体I类内含子编码一种成熟酶，并且在杂交中可移动。

A mitochondrial group-I intron in fission yeast encodes a maturase and is mobile in crosses.

作者信息

Schäfer B, Wilde B, Massardo D R, Manna F, Del Giudice L, Wolf K

机构信息

Institut für Biologie IV (Mikrobiologie), Rheinisch-Westfälische Technische Hochschule, Aachen, Germany.

出版信息

Curr Genet. 1994 Apr;25(4):336-41. doi: 10.1007/BF00351487.

DOI:10.1007/BF00351487
PMID:8082176
Abstract

The open reading frame in the first intron of the mitochondrial gene encoding subunit I of cytochrome c oxidase encodes a maturase and stimulates homologous recombination in Escherichia coli. In this paper, we demonstrate that this intron is mobile in crosses, indicating that it also encodes an endonuclease. This is the first report on an intron which possesses mobility and acts as a maturase.

摘要

细胞色素c氧化酶亚基I的线粒体基因第一个内含子中的开放阅读框编码一种成熟酶，并在大肠杆菌中刺激同源重组。在本文中，我们证明了这个内含子在杂交中是可移动的，这表明它也编码一种内切核酸酶。这是关于一个具有可移动性并作为成熟酶的内含子的首次报道。

相似文献

1
A mitochondrial group-I intron in fission yeast encodes a maturase and is mobile in crosses.裂殖酵母中的一个线粒体I类内含子编码一种成熟酶，并且在杂交中可移动。
Curr Genet. 1994 Apr;25(4):336-41. doi: 10.1007/BF00351487.
2
A latent intron-encoded maturase is also an endonuclease needed for intron mobility.一种潜在的内含子编码成熟酶也是内含子移动所需的一种核酸内切酶。
Cell. 1989 Feb 10;56(3):421-30. doi: 10.1016/0092-8674(89)90245-6.
3
The mitochondrial genome of Schizosaccharomyces pombe. Stimulation of intra-chromosomal recombination in Escherichia coli by the gene product of the first cox1 intron.粟酒裂殖酵母的线粒体基因组。第一个cox1内含子的基因产物对大肠杆菌染色体内重组的刺激作用。
Curr Genet. 1991 Apr;19(4):295-9. doi: 10.1007/BF00355058.
4
Splicing-defective mutants of the yeast mitochondrial COXI gene can be corrected by transformation with a hybrid maturase gene.酵母线粒体COXI基因的剪接缺陷型突变体可通过用杂交成熟酶基因转化来校正。
Proc Natl Acad Sci U S A. 1991 Jul 1;88(13):5592-6. doi: 10.1073/pnas.88.13.5592.
5
A bacterial group II intron encoding reverse transcriptase, maturase, and DNA endonuclease activities: biochemical demonstration of maturase activity and insertion of new genetic information within the intron.编码逆转录酶、成熟酶和DNA内切核酸酶活性的细菌II类内含子：成熟酶活性的生化证明以及内含子内新遗传信息的插入
Genes Dev. 1997 Nov 1;11(21):2910-24. doi: 10.1101/gad.11.21.2910.
6
Connections between RNA splicing and DNA intron mobility in yeast mitochondria: RNA maturase and DNA endonuclease switching experiments.酵母线粒体中RNA剪接与DNA内含子移动性之间的联系：RNA成熟酶和DNA内切酶转换实验。
Mol Cell Biol. 1992 Feb;12(2):696-705. doi: 10.1128/mcb.12.2.696-705.1992.
7
Mitochondrial introns as mobile genetic elements: the role of intron-encoded proteins.作为可移动遗传元件的线粒体内含子：内含子编码蛋白的作用。
Basic Life Sci. 1986;40:5-27. doi: 10.1007/978-1-4684-5251-8_2.
8
The mobile group I intron 3 alpha of the yeast mitochondrial COXI gene encodes a 35-kDa processed protein that is an endonuclease but not a maturase.酵母线粒体COXI基因的Ⅰ组内含子3α移动元件编码一种35kDa的加工蛋白，该蛋白是一种内切核酸酶而非成熟酶。
J Biol Chem. 1995 Jun 30;270(26):15563-70. doi: 10.1074/jbc.270.26.15563.
9
Homologous maturase-like proteins are encoded within the group I introns in different mitochondrial genes specifying Yarrowia lipolytica cytochrome c oxidase subunit 3 and Saccharomyces cerevisiae apocytochrome b.同源成熟酶样蛋白编码于不同线粒体基因中的I类内含子内，这些基因分别指定解脂耶氏酵母细胞色素c氧化酶亚基3和酿酒酵母脱辅基细胞色素b。
Curr Genet. 1994 Nov-Dec;26(5-6):377-81. doi: 10.1007/BF00309922.
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Site-specific DNA endonuclease and RNA maturase activities of two homologous intron-encoded proteins from yeast mitochondria.来自酵母线粒体的两种同源内含子编码蛋白的位点特异性DNA内切核酸酶和RNA成熟酶活性
Cell. 1989 Feb 10;56(3):431-41. doi: 10.1016/0092-8674(89)90246-8.

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Revealing the high variability on nonconserved core and mobile elements of Austropuccinia psidii and other rust mitochondrial genomes.揭示 Austropuccinia psidii 和其他锈菌线粒体基因组中非保守核心和移动元件的高度变异性。
PLoS One. 2021 Mar 11;16(3):e0248054. doi: 10.1371/journal.pone.0248054. eCollection 2021.
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Intraspecific Diversity of Fission Yeast Mitochondrial Genomes.裂殖酵母线粒体基因组的种内多样性。
Genome Biol Evol. 2019 Aug 1;11(8):2312-2329. doi: 10.1093/gbe/evz165.
3
The brown algae Pl.LSU/2 group II intron-encoded protein has functional reverse transcriptase and maturase activities.

本文引用的文献

1
I-Sce III an intron-encoded DNA endonuclease from yeast mitochondria. Asymmetrical DNA binding properties and cleavage reaction.I-Sce III，一种来自酵母线粒体的内含子编码DNA内切酶。不对称DNA结合特性及切割反应。
Nucleic Acids Res. 1993 Aug 11;21(16):3683-9. doi: 10.1093/nar/21.16.3683.
2
Introns as mobile genetic elements.作为可移动遗传元件的内含子。
Annu Rev Biochem. 1993;62:587-622. doi: 10.1146/annurev.bi.62.070193.003103.
3
Comparison of fungal mitochondrial introns reveals extensive homologies in RNA secondary structure.真菌线粒体内含子的比较揭示了RNA二级结构中广泛的同源性。
棕藻 Pl.LSU/2 组 II 内含子编码蛋白具有功能性逆转录酶和成熟酶活性。
PLoS One. 2013;8(3):e58263. doi: 10.1371/journal.pone.0058263. Epub 2013 Mar 11.
4
Group I introns and inteins: disparate origins but convergent parasitic strategies.第一类内含子和蛋白质内含子：起源不同但寄生策略趋同。
J Bacteriol. 2009 Oct;191(20):6193-202. doi: 10.1128/JB.00675-09. Epub 2009 Aug 7.
5
Optimization of in vivo activity of a bifunctional homing endonuclease and maturase reverses evolutionary degradation.双功能归巢核酸内切酶和成熟酶体内活性的优化逆转了进化退化。
Nucleic Acids Res. 2009 Feb;37(3):877-90. doi: 10.1093/nar/gkn1007. Epub 2008 Dec 22.
6
Transcription and RNA-processing in fission yeast mitochondria.裂殖酵母线粒体中的转录与RNA加工
RNA. 2005 May;11(5):785-95. doi: 10.1261/rna.7252205. Epub 2005 Apr 5.
7
Intragenic suppressors that restore the activity of the maturase encoded by the second intron of the Saccharomyces cerevisiae cyt b gene.恢复酿酒酵母细胞色素b基因第二个内含子所编码成熟酶活性的基因内抑制子。
Curr Genet. 2004 Aug;46(2):67-71. doi: 10.1007/s00294-004-0509-5. Epub 2004 May 27.
8
Genetic conservation versus variability in mitochondria: the architecture of the mitochondrial genome in the petite-negative yeast Schizosaccharomyces pombe.线粒体中的遗传保守性与变异性：小菌落阴性酵母粟酒裂殖酵母中线粒体基因组的结构
Curr Genet. 2003 Aug;43(5):311-26. doi: 10.1007/s00294-003-0404-5. Epub 2003 May 9.
9
Homing endonucleases: structural and functional insight into the catalysts of intron/intein mobility.归巢内切酶：对内含子/内含肽移动性催化剂的结构与功能洞察
Nucleic Acids Res. 2001 Sep 15;29(18):3757-74. doi: 10.1093/nar/29.18.3757.
10
Unusual evolutionary history of the tRNA splicing endonuclease EndA: relationship to the LAGLIDADG and PD-(D/E)XK deoxyribonucleases.tRNA剪接内切酶EndA不同寻常的进化史：与LAGLIDADG和PD-(D/E)XK脱氧核糖核酸酶的关系
Protein Sci. 2001 Mar;10(3):656-60. doi: 10.1110/ps.37101.
Biochimie. 1982 Oct;64(10):867-81. doi: 10.1016/s0300-9084(82)80349-0.
4
Internal structure of a mitochondrial intron of Aspergillus nidulans.构巢曲霉线粒体内含子的内部结构。
Proc Natl Acad Sci U S A. 1982 Oct;79(20):6332-6. doi: 10.1073/pnas.79.20.6332.
5
Two intron sequences in yeast mitochondrial COX1 gene: homology among URF-containing introns and strain-dependent variation in flanking exons.酵母线粒体COX1基因中的两个内含子序列：含URF的内含子之间的同源性以及侧翼外显子的菌株依赖性变异。
Cell. 1983 Feb;32(2):379-89. doi: 10.1016/0092-8674(83)90457-9.
6
Single base substitution in an intron of oxidase gene compensates splicing defects of the cytochrome b gene.氧化酶基因内含子中的单碱基替换补偿了细胞色素b基因的剪接缺陷。
Nature. 1982 Aug 12;298(5875):628-32. doi: 10.1038/298628a0.
7
Critical sequences within mitochondrial introns: pleiotropic mRNA maturase and cis-dominant signals of the box intron controlling reductase and oxidase.线粒体内含子中的关键序列：多效性mRNA成熟酶以及控制还原酶和氧化酶的盒式内含子的顺式显性信号。
Cell. 1982 Apr;28(4):721-32. doi: 10.1016/0092-8674(82)90051-4.
8
Molecular basis of the 'box effect', A maturase deficiency leading to the absence of splicing of two introns located in two split genes of yeast mitochondrial DNA.“盒效应”的分子基础，一种成熟酶缺陷导致酵母线粒体DNA两个分裂基因中两个内含子缺失剪接。
Eur J Biochem. 1984 Oct 1;144(1):85-93. doi: 10.1111/j.1432-1033.1984.tb08434.x.
9
The mitochondrial genome of the fission yeast Schizosaccharomyces pombe. 2. Localization of genes by interspecific hybridization in strain ade7-50h- and cloning of the genome in small fragments.裂殖酵母粟酒裂殖酵母的线粒体基因组。2. 通过种间杂交在ade7-50h-菌株中定位基因以及将基因组克隆为小片段。
Mol Gen Genet. 1984;196(3):465-72. doi: 10.1007/BF00436194.
10
A protein required for splicing group I introns in Neurospora mitochondria is mitochondrial tyrosyl-tRNA synthetase or a derivative thereof.在粗糙脉孢菌线粒体中剪接I组内含子所需的一种蛋白质是线粒体酪氨酰-tRNA合成酶或其衍生物。
Cell. 1987 Jul 31;50(3):331-45. doi: 10.1016/0092-8674(87)90488-0.