小剂量利多卡因的脑和心脏毒性
Cerebral and cardiac toxicity of a small dose of lignocaine.
作者信息
Klein H O, Jutrin I, Kaplinsky E
出版信息
Br Heart J. 1975 Jul;37(7):775-8. doi: 10.1136/hrt.37.7.775.
Abstract
A patient is reported in whom an intravenous bolus injection of 50 mg lignocaine produced extreme sinus bradycardia (rate 14 to 20/min). Only 2 patients with such a response to a similarly small dose have been previously reported, but these reports indicate clearly that careful electrocardiographic monitoring is advisable when lignocaine is administered.
摘要
据报道，一名患者静脉推注50毫克利多卡因后出现极度窦性心动过缓（心率14至20次/分钟）。此前仅报道过2例对同样小剂量有这种反应的患者，但这些报道清楚地表明，使用利多卡因时建议进行仔细的心电图监测。
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