Garner L, Stirt J A, Finholt D A
Can Anaesth Soc J. 1985 Jul;32(4):425-8. doi: 10.1007/BF03011356.
A 14-day-old infant received intravenous lidocaine (2 mg X kg-1) at the conclusion of cataract surgery to prevent coughing from tracheal tube stimulation. Within 30 seconds the infant developed high-grade AV heart block and a ventricular rate of 40. Following brief resuscitation efforts, the patient had a normal cardiac rhythm, blood pressure and respiratory pattern. Intravenous lidocaine may be followed by major disturbances in cardiac rhythm and rate. Cautious titration of small doses should decrease the potential for adverse effects.
一名14天大的婴儿在白内障手术结束时接受了静脉注射利多卡因(2毫克/千克),以防止气管导管刺激引起咳嗽。30秒内,婴儿出现高度房室传导阻滞,心室率为40次/分。经过短暂的复苏努力,患者的心律、血压和呼吸模式恢复正常。静脉注射利多卡因后可能会出现严重的心律和心率紊乱。谨慎滴定小剂量应可降低不良反应的可能性。