Sun B Z, Wang X G, Wang Y L
Qingdao Municipal Hospital.
Zhonghua Fu Chan Ke Za Zhi. 1994 Mar;29(3):141-3, 189.
Fifty gram oral glucose challenge test (50g GCT) was performed, as a screening test of diabetes mellitus (DM), in 289 pregnant women, and further, a 75g oral glucose tolerance test (OGTT) was done in those women with glucose level > 7.78 mmol/L. The results showed that 49 women had a glucose level > 7.78 mmol/L (16.96%), among whom 15 (5.19%) were identified as having gestational impaired glucose tolerance (GIGT), and 5 (1.73%) had gestational diabetes mellitus (GDM) as diagnosed by 75g OGTT. The prevalence of PIH, premature rupture of membrane, fetal macrosomia, cesarean section, perinatal morbidity were higher in GIGT and GDM mothers and there was a positive correlation between glucose level of 50g GCT and the birth weight of newborns. It suggested that 50g GCT may be a preferable screening test for GDM since it is simple and cheap with high sensitivity and specificity.
对289名孕妇进行了50克口服葡萄糖耐量试验（50g GCT），作为糖尿病（DM）的筛查试验，对于血糖水平>7.78 mmol/L的孕妇进一步进行了75克口服葡萄糖耐量试验（OGTT）。结果显示，49名女性血糖水平>7.78 mmol/L（16.96%），其中15名（5.19%）被诊断为妊娠期糖耐量受损（GIGT），5名（1.73%）经75g OGTT诊断为妊娠期糖尿病（GDM）。GIGT和GDM母亲发生妊娠期高血压疾病、胎膜早破、巨大儿、剖宫产、围产期发病率较高，50g GCT血糖水平与新生儿出生体重呈正相关。这表明50g GCT可能是一种较好的GDM筛查试验，因为它简单、便宜，具有较高的敏感性和特异性。
