Yang R M, Gu C Y, Li T X
Yanan Hospital, Kuming.
Zhonghua Fu Chan Ke Za Zhi. 1994 Mar;29(3):144-6, 189.
Perinatal cytomegalovirus (CMV) infection was studied, using method of CMV-IgM ELISA, in 256 pregnant women at different periods and in the cord blood of 84 babies born by CMV positive mothers. Results showed that in 42 cases at early and midtrimester pregnancy, 17 were CMV-IgM positive with an infection rate of 40.48%. Among the 214 women at late pregnancy, 84 were positive (39.25%). There was a higher prevalence of perinatal morbidity, neonatal asphyxia, malformation, intrauterine death, and poor obstetrical outcome in the CMV positive mothers as compared with the CMV negative group (P < 0.01). This study showed that the presence of CMV-IgM indicated a recent or recurrent CMV infection during pregnancy and the babies should be carefully monitored.
采用巨细胞病毒-IgM酶联免疫吸附测定法，对256例不同孕周的孕妇及84例巨细胞病毒阳性母亲所分娩婴儿的脐血进行了围产期巨细胞病毒感染研究。结果显示，孕早期和孕中期的42例孕妇中，17例巨细胞病毒-IgM阳性，感染率为40.48%。孕晚期的214例孕妇中，84例阳性（39.25%）。与巨细胞病毒阴性组相比，巨细胞病毒阳性母亲的围产期发病率、新生儿窒息、畸形、宫内死亡及不良产科结局的发生率更高（P<0.01）。本研究表明，巨细胞病毒-IgM的存在表明孕期近期或反复感染巨细胞病毒，应对婴儿进行密切监测。
