Nicolai A, Lazzarino L G
Eur Neurol. 1994;34(4):230-5. doi: 10.1159/000117045.
The authors report the cases of 2 patients with extensive brain calcifications after thyroidectomy, showing behavioral and cognitive changes suggesting a subcortical dementia syndrome. On the basis of clinical, neuroradiologic and SPECT features they discuss the role of the brain calcifications in the pathophysiology of associated cognitive disorders and the putative mechanisms for the observed neuropsychological disorders.
作者报告了2例甲状腺切除术后出现广泛脑钙化的病例,这些病例表现出行为和认知改变,提示存在皮质下痴呆综合征。基于临床、神经放射学和单光子发射计算机断层扫描(SPECT)特征,他们讨论了脑钙化在相关认知障碍病理生理学中的作用以及所观察到的神经心理障碍的可能机制。