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一组呼气酒精数据中明显丙酮的频率:统计处理及法医学意义

The frequency of apparent acetone in a group of breath alcohol data: statistical treatment and forensic implications.

作者信息

Gullberg R G

机构信息

Washington State Patrol, Breath Test Section, Seattle 98102.

出版信息

Forensic Sci Int. 1994 Jun 28;67(1):65-72. doi: 10.1016/0379-0738(94)90414-6.

DOI:10.1016/0379-0738(94)90414-6
PMID:8082863
Abstract

The potential presence of interfering substances (specifically acetone) is a concern in the forensic reporting of evidential breath alcohol analysis. As a result, manufacturers have designed instruments to monitor its occurrence through various hardware and software features. This paper is a retrospective study where 35,945 duplicate breath samples from BAC Verifier DataMaster instruments are evaluated for the frequency of 'interferant' values > or = 0.010 g per 210 l ethanol equivalent. A total of 264 (0.74%) of the duplicate samples had an interferant value on the first sample only, while 235 (0.66%) had interferant values on the second samples only. A total of 77 (0.21%) of the duplicate samples had in interferant values on both breath samples and only in these cases could the presence of measurable acetone even be considered. The occurrence of interferant results appeared also to be instrument-dependent with 55.7% of the interferant values on the first breath sample occurring on nine (13%) of the instruments displaying such results. The occurrences of interferant values on the first breath sample did not conform to the Poisson distribution (P < 0.0001) for the instrument with the largest number of occurrences, while there was conformance for other instruments evaluated. Finally, approximately 23 cases (0.064%) remained where the presence of acetone is a possible consideration. Several issues are presented that the forensic scientist should consider when attempting to explain an apparent interferant result in an individual case. It should be remembered that measurement results need to be interpreted in their context, and data analysis concerning an instrument's performance should be considered.

摘要

在证据性呼气酒精分析的法医报告中,干扰物质(特别是丙酮)的潜在存在是一个令人担忧的问题。因此,制造商设计了仪器,通过各种硬件和软件功能来监测其出现情况。本文是一项回顾性研究,对来自BAC Verifier DataMaster仪器的35945份重复呼气样本进行评估,以确定“干扰物”值≥0.010克每210升乙醇当量的频率。共有264份(0.74%)重复样本仅在第一个样本上有干扰物值,而235份(0.66%)仅在第二个样本上有干扰物值。共有77份(0.21%)重复样本在两个呼气样本上都有干扰物值,只有在这些情况下才会考虑是否存在可测量的丙酮。干扰结果的出现似乎也与仪器有关,第一个呼气样本上55.7%的干扰物值出现在显示此类结果的九台(13%)仪器上。对于出现次数最多的仪器,第一个呼气样本上干扰物值的出现不符合泊松分布(P<0.0001),而对于其他评估的仪器则符合。最后,大约有23个案例(0.064%)仍有可能存在丙酮。本文提出了一些问题,供法医科学家在试图解释个别案例中明显的干扰结果时考虑。应该记住,测量结果需要结合其背景进行解释,并且应该考虑有关仪器性能的数据分析。

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The frequency of apparent acetone in a group of breath alcohol data: statistical treatment and forensic implications.一组呼气酒精数据中明显丙酮的频率:统计处理及法医学意义
Forensic Sci Int. 1994 Jun 28;67(1):65-72. doi: 10.1016/0379-0738(94)90414-6.
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Isopropanol interference with breath alcohol analysis: a case report.异丙醇对呼气酒精分析的干扰:一例报告。
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