Kashiyama T, Fujita A, Watanabe A, Suzuki A, Nakamura K, Kimura H
Department of Respiratory Service, Tokyo Metropolitan Fuchu Hospital, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1994 May;32(5):502-6.
Hodgkin's disease rarely involves bones and lungs without causing marked lymph node enlargement. The case of a 36 year old man, who initially presented with vertebral lesions and a solitary nodule in the lung, is reported. At the initial presentation, no apparent lymph node enlargement was observed. Pathological examination of the specimens obtained at vertebral surgery and needle biopsy of the lung suggested a presumptive diagnosis of Histiocytosis X. However, a definite diagnosis of the Hodgkin's disease was made by biopsy of a cervical lymph node which newly enlarged about two years after his initial presentation. This case suggests variability in the clinical feature of Hodgkin's disease.
霍奇金病很少累及骨骼和肺部而不引起明显的淋巴结肿大。本文报告了一名36岁男性患者的病例,该患者最初表现为脊柱病变和肺部单个结节。初次就诊时,未观察到明显的淋巴结肿大。对脊柱手术获取的标本及肺部穿刺活检标本进行病理检查,初步诊断为组织细胞增多症X。然而,在初次就诊约两年后,通过对新出现肿大的颈部淋巴结进行活检,确诊为霍奇金病。该病例提示霍奇金病临床特征存在变异性。