Jurkiewicz J, Czernicki Z, Berdyga J, Uchman G
Kliniki Neurochirurgii Instytutu Centrum Medycyny Doświadczalnej i Klinicznej PAN, Warszawie.
Neurol Neurochir Pol. 1994 May-Jun;28(3):363-9.
A new CSF circulation diagnostic procedure is presented. The method is called three-phase infusion test. In phase I the CSF absorption mechanisms were tested within ICP range below 20 mmHg and then the infusion rate of 0.06 ml/min was applied. In phase II the high infusion rate (0.3 ml/min) was used and high ICP increase occurred. This part of the study provided data concerning the ability of alternative CSF outflow routes. In phase III again low infusion rate (0.06 ml/min) was applied. The obtained CSF outflow data in phase III were significantly lower than in phase I. This is the so called persistent outflow facilitation phenomenon. The method described, covering different mechanisms of CSF absorption, enables the complex evaluation of CSF outflow sufficiency.
提出了一种新的脑脊液循环诊断程序。该方法称为三相输注试验。在第一阶段,在颅内压低于20 mmHg的范围内测试脑脊液吸收机制,然后应用0.06 ml/min的输注速率。在第二阶段,使用高输注速率(0.3 ml/min),颅内压出现大幅升高。该研究的这一部分提供了有关脑脊液替代流出途径能力的数据。在第三阶段,再次应用低输注速率(0.06 ml/min)。第三阶段获得的脑脊液流出数据明显低于第一阶段。这就是所谓的持续流出促进现象。所描述的方法涵盖了脑脊液吸收的不同机制,能够对脑脊液流出充足性进行综合评估。