Fava G A
Department of Psychology, University of Bologna, Italy.
Psychosomatics. 1994 Jul-Aug;35(4):341-53. doi: 10.1016/S0033-3182(94)71755-2.
This is a review of psychosomatic interactions between affective disorders (depressive and anxiety disturbances, irritable mood) and endocrine disease. Particular reference is made to stressful life events in the pathogenesis of endocrine disease, psychopathology of hormonal disturbances, and pathophysiology of hypothalamic-pituitary-adrenal axis function in depression and Cushing's disease. These psychosomatic interactions may lead to appraisal of common etiological mechanisms in endocrine and psychiatric disorders, of the value of retaining the category of organic affective syndromes in psychiatric classification, and of the need for research on quality-of-life measures in endocrine disease. The establishment of "psychoendocrine units," where both endocrinologists and psychiatrists should work, is advocated. Such psychoendocrine units may serve and benefit clinical populations who currently defy traditional medical subdivisions.
本文综述了情感障碍（抑郁和焦虑障碍、易怒情绪）与内分泌疾病之间的心身相互作用。特别提及了应激性生活事件在内分泌疾病发病机制中的作用、激素紊乱的精神病理学，以及抑郁症和库欣病中下丘脑-垂体-肾上腺轴功能的病理生理学。这些心身相互作用可能促使人们对内分泌和精神疾病的常见病因机制、在精神疾病分类中保留器质性情感综合征这一类别价值，以及内分泌疾病生活质量测量研究的必要性进行评估。文中提倡建立“心理内分泌科”，内分泌科医生和精神科医生都应在此工作。这样的心理内分泌科可能会为目前不符合传统医学细分的临床人群提供服务并使其受益。
