Pérez J A, Silva R, del Pozo M, Henning E
Instituto de Cirugía, Facultad de Medicina, Universidad Austral de Chile, Valdivia.
Rev Med Chil. 1994 Feb;122(2):201-5.
The association of diffuse hyperthyroid goiter and thyroid cancer is rare and interesting, considering that both diseases affect the same organ but have different pathogenesis and prognosis. We report two patients that consulted for diffuse hyperthyroid goiter and were subjected to a subtotal bilateral thyroidectomy due to antithyroid drug failure. Pathological study revealed the coexistence of diffuse gland hyperplasia and a papillary thyroid carcinoma of less than 7 mm phi. In both cases, the thyroid remanent was ablated with radioactive iodine during the postoperative period and thyroid substitution was started.
弥漫性甲状腺功能亢进性甲状腺肿与甲状腺癌的关联罕见且有趣,因为这两种疾病虽影响同一器官,但发病机制和预后不同。我们报告了两名因弥漫性甲状腺功能亢进性甲状腺肿前来就诊的患者,由于抗甲状腺药物治疗失败,他们接受了双侧甲状腺次全切除术。病理研究显示弥漫性腺体增生与直径小于7毫米的甲状腺乳头状癌并存。在这两个病例中,术后均用放射性碘对甲状腺残余组织进行了消融,并开始了甲状腺替代治疗。