毒素灭活与抗原稳定：甲醛的两种不同用途。
Toxin inactivation and antigen stabilization: two different uses of formaldehyde.
作者信息
Rappuoli R
机构信息
IRIS, Immunobiological Research Institute Siena, Italy.
出版信息
Vaccine. 1994 May;12(7):579-81. doi: 10.1016/0264-410x(94)90259-3.
PMID:8085372
Abstract
Since the 1920s, when Ramon discovered the detoxifying properties of formaldehyde, this compound has been used to inactivate toxins, whole bacterial cells and viruses. With the development of vaccines that are detoxified by genetic manipulation, formaldehyde has a new role as a stabilizer of such genetically detoxified antigens.
摘要
自20世纪20年代拉蒙发现甲醛的解毒特性以来，这种化合物一直被用于使毒素、全细菌细胞和病毒失活。随着通过基因操作进行解毒的疫苗的发展，甲醛作为这种基因解毒抗原的稳定剂有了新的作用。
Zotero 插件