Ohlms L A, McGill T, Healy G B
Department of Otolaryngology, Children's Hospital, Boston, Massachusetts 02115.
Ann Otol Rhinol Laryngol. 1994 Sep;103(9):686-92. doi: 10.1177/000348949410300905.
Malignant laryngeal neoplasms in children are uncommon and present diagnostic and therapeutic challenges. A 15-year retrospective review of laryngeal tumors at our institution identified four patients with malignant neoplasms. These children, 7 months to 16 years of age, were treated for squamous cell carcinoma, choriocarcinoma, rhabdomyosarcoma, and primitive neuroectodermal tumor. This report details these cases, emphasizing diagnostic approaches, treatment decisions (medical oncologic management, surgical resection), and rehabilitation measures for postlaryngectomy communication. A multi-institutional pediatric head and neck tumor registry would be a useful reference to assist with individual treatment decisions.
儿童喉恶性肿瘤并不常见，在诊断和治疗方面存在挑战。对我院15年的喉肿瘤病例进行回顾性分析，确定了4例患有恶性肿瘤的患儿。这些儿童年龄在7个月至16岁之间，分别接受了鳞状细胞癌、绒毛膜癌、横纹肌肉瘤和原始神经外胚层肿瘤的治疗。本报告详细介绍了这些病例，重点强调了诊断方法、治疗决策（医学肿瘤学管理、手术切除）以及喉切除术后交流的康复措施。多机构儿童头颈肿瘤登记处将有助于为个体治疗决策提供有用参考。
