Erickson K L, Montagna W
J Invest Dermatol. 1975 Sep;65(3):279-84. doi: 10.1111/1523-1747.ep12598343.
Except for the face, eyelids, friction surfaces, and lips, the epidermis of the rhesus monkey contains no discernible melanocytes. After ultraviolet irradiation, however, dopa-positive dendritic cells appeared. With daily sequential irradiation, the number of histochemically demonstrable dopa-positive dendritic cells peaked after 30 exposures, then declined to a basal level which was maintained for the duration of the experiment (216 exposures or 43 weeks). Pigment cells can be restimulated by shading part of the irradiated area and then reirradiating after 3 months. While shaded, dopa-positive cells disappeared; but when reirradiated, they reappeared, increased, then declined again to a basal level. These melanocytes, unlike those in other primates, require high threshold levels of irradiation to produce a response, have a definite period during which they are active, and transfer very little melanin to the surrounding keratinocytes. Long-term ultraviolet irradiation has no discernible effect on dermal pigment-containing cells.
除面部、眼睑、摩擦面和嘴唇外，恒河猴的表皮中没有可辨认的黑素细胞。然而，紫外线照射后，出现了多巴阳性的树突状细胞。每日连续照射时，组织化学可显示的多巴阳性树突状细胞数量在30次照射后达到峰值，然后下降到基础水平，并在实验期间（216次照射或43周）维持该水平。色素细胞可通过遮蔽部分照射区域，3个月后再照射来重新刺激。遮蔽期间，多巴阳性细胞消失；但再次照射时，它们又会出现，数量增加，然后再次下降到基础水平。这些黑素细胞与其他灵长类动物的黑素细胞不同，需要高阈值水平的照射才能产生反应，有一个明确的活跃期，并且向周围角质形成细胞转移的黑色素很少。长期紫外线照射对真皮含色素细胞没有明显影响。
