Wiener A S, Socha W W, Niemann W, Moor-Jankowski J
J Med Primatol. 1975;4(3):179-87.
The current status of erythroblastosis fetalis in man and in animals is briefly reviewed with emphasis on present knowledge of nonhuman primates as models for the disease. Our studies in crab-eating macaques indicate that presence in a mother's serum of potent antibodies reactive for red cells for her fetus will not necessarily cause erythroblastosis; in one case the maternal antibodies did not penetrate the placental barrier, and in two cases although the fetal red cells were maximally antibody-coated, they remained undamaged and the disease failed to develop.
本文简要回顾了人类和动物胎儿成红细胞增多症的现状，重点阐述了以非人类灵长类动物作为该疾病模型的现有知识。我们对食蟹猕猴的研究表明，母亲血清中存在对其胎儿红细胞具有反应性的强效抗体，不一定会导致胎儿成红细胞增多症；在一个案例中，母体抗体未穿透胎盘屏障，而在另外两个案例中，尽管胎儿红细胞被抗体最大限度地包被，但它们并未受损，疾病也未发展。
