乳酸脱氢酶-5（LDH-5）从近交系小鼠血液循环中的清除与它和巨噬细胞的结合相关。
Clearance of LDH-5 from the circulation of inbred mice correlates with binding to macrophages.
作者信息
Hayashi T, Notkins A L
机构信息
Laboratory of Veterinary Pathology, Yamaguchi University, Japan.
出版信息
Int J Exp Pathol. 1994 Jun;75(3):165-8.
Abstract
Flow cytometry showed that the enzyme lactate dehydrogenase (LDH-5) binds to peritoneal macrophages. The degree of binding appears to be genetically controlled and varies depending on the inbred strain of mouse. The rate at which LDH-5 is cleared from the circulation correlates with the degree of binding to macrophages. These findings suggest that the binding of LDH-5 to macrophages may serve as an in-vitro index of enzyme clearance.
摘要
流式细胞术显示，乳酸脱氢酶（LDH - 5）与腹膜巨噬细胞结合。结合程度似乎受基因控制，并因小鼠的近交系不同而有所差异。LDH - 5从循环中清除的速率与巨噬细胞的结合程度相关。这些发现表明，LDH - 5与巨噬细胞的结合可能作为酶清除的体外指标。
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IMPAIRED CLEARANCE OF ENZYMES IN MICE INFECTED WITH THE LACTIC DEHYDROGENASE AGENT.感染乳酸脱氢酶病毒的小鼠体内酶清除功能受损。
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Enzymatic and immunologic alterations in mice infected with lactic dehydrogenase virus.感染乳酸脱氢酶病毒的小鼠的酶学和免疫学改变
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5
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7
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