Limmer J, Gortner L, Kelsch G, Schütze F, Berger D
Department of Surgery, University of Ulm, Germany.
Acta Paediatr Suppl. 1994;396:65-9. doi: 10.1111/j.1651-2227.1994.tb13247.x.
From 1980 to 1991, 70 preterm and 20 term infants suffering from necrotizing enterocolitis (NEC) were treated at the University of Ulm hospitals. NEC was primarily suspected from clinical signs. The diagnosis was established by plain abdominal X-rays, infection markers and abdominal paracentesis. Indication for surgery resulted from paracentesis, from radiologically proven perforation, from ileus symptoms and from rapid clinical deterioration; 44 preterm and 7 term infants underwent surgery. Bowel resections were performed in 5 of the term and in 16 of the preterm infants. An enterostomy was fashioned in 33 cases. Total necrosis of the gut was apparent in 8 infants. A continuous peritoneal lavage was performed in 34 babies. One term and 18 preterm babies, all with a birth weight less than 1000 g, died. This results in a NEC-related overall mortality of 19%.
1980年至1991年期间,乌尔姆大学医院对70例早产儿和20例足月儿进行了坏死性小肠结肠炎(NEC)治疗。NEC主要通过临床症状怀疑。诊断通过腹部平片、感染指标和腹腔穿刺确定。手术指征源于腹腔穿刺、放射学证实的穿孔、肠梗阻症状和快速的临床恶化;44例早产儿和7例足月儿接受了手术。5例足月儿和16例早产儿进行了肠切除术。33例进行了肠造口术。8例婴儿出现肠道全坏死。34例婴儿进行了持续腹腔灌洗。1例足月儿和18例早产儿死亡,均出生体重低于1000g。这导致NEC相关的总死亡率为19%。