Fasching G, Höllwarth M E, Schmidt B, Mayr J
Department of Pediatric Surgery, University of Graz Medical School, Austria.
Acta Paediatr Suppl. 1994;396:62-4. doi: 10.1111/j.1651-2227.1994.tb13246.x.
Very-low-birthweight (VLBW) neonates are more prone to complications and death than term infants are. In a 15-year period, 19 neonates with VLBW were operated on for necrotizing enterocolitis (NEC). Indications for operation were pneumoperitoneum in 12 and deterioration of general condition in 7. Bowel resection and intestinal diversion was performed in 12, a lateral enterostomy at the site of perforation was created in 5, and 2 neonates with necrosis of the whole bowel underwent an exploratory laparotomy without any further surgical treatment. Surgical complications were found in one-third of the patients. The mortality rate was significantly higher when the ileum was affected. The survival rate was 68%. Prior to 1984 the survival rate was 37% (3/8); subsequently, it has improved to 91% (10/11) as a result of improved intensive therapy.
极低出生体重(VLBW)新生儿比足月儿更容易出现并发症和死亡。在15年期间,19例极低出生体重新生儿因坏死性小肠结肠炎(NEC)接受了手术。手术指征为12例出现气腹,7例全身状况恶化。12例行肠切除和肠造口术,5例在穿孔部位行侧方肠造口术,2例全肠坏死的新生儿接受了剖腹探查术,未进行进一步的手术治疗。三分之一的患者出现手术并发症。回肠受累时死亡率显著更高。存活率为68%。1984年以前,存活率为37%(3/8);随后,由于强化治疗的改善,存活率提高到了91%(10/11)。