Fleming I D, Fleming M D
University of Tennessee Center for the Health Sciences, Department of Surgery, Methodist Health Systems, Memphis.
Cancer. 1994 Oct 1;74(7 Suppl):2160-4. doi: 10.1002/1097-0142(19941001)74:7+<2160::aid-cncr2820741726>3.0.co;2-o.
With the aging of the American population, more older women are being diagnosed with breast cancer. With the possible exception of women under 40 years of age, there is no clear evidence of a biologic or clinical difference between breast cancer in younger and older aged groups. Breast cancer is diagnosed at a more advanced stage in older women. Elderly women with breast cancer frequently are treated with less than standard therapy and are less often included in clinical trials. With the exception of specific comorbid conditions that preclude anesthesia and surgery, older women tolerate breast surgery as well as younger women. The results of good surgical and adjuvant therapy for elderly women are as good as those for younger women. Older women with breast cancer deserve the most effective screening, diagnosis, and surgical treatment available.
随着美国人口老龄化,越来越多的老年女性被诊断出患有乳腺癌。除了40岁以下的女性外,没有明确证据表明年轻和老年乳腺癌患者在生物学或临床方面存在差异。老年女性乳腺癌往往在更晚期被诊断出来。患有乳腺癌的老年女性经常接受低于标准的治疗,而且较少被纳入临床试验。除了特定的合并症会妨碍麻醉和手术外,老年女性对乳房手术的耐受性与年轻女性一样好。老年女性接受良好的手术和辅助治疗的效果与年轻女性相同。患有乳腺癌的老年女性应该得到现有的最有效的筛查、诊断和手术治疗。