Nowack W J, Jordan R
Department of Neurology, University of South Alabama, Mobile 36617.
Clin Electroencephalogr. 1994 Jul;25(3):110-4. doi: 10.1177/155005949402500308.
Propofol is a relatively new anesthetic agent used in outpatient surgery. Some investigators use it in the treatment of status epilepticus and in epilepsy surgery and have concluded that propofol has an anticonvulsant effect. Cases of seizure-like behaviors, myoclonus and opisthotonus following propofol anesthesia have been reported. Although rare, official warnings about this association have been issued. Different EEG abnormalities, and no abnormality, have been associated with propofol. We report a case of a healthy man who developed nonconvulsive seizures and generalized paroxysmal fast activity in his EEG following use of propofol for anesthesia.
丙泊酚是一种用于门诊手术的相对较新的麻醉剂。一些研究人员将其用于治疗癫痫持续状态和癫痫手术，并得出结论认为丙泊酚具有抗惊厥作用。有报告称，丙泊酚麻醉后出现了癫痫样行为、肌阵挛和角弓反张的病例。尽管罕见，但已发布了关于这种关联的官方警告。丙泊酚与不同的脑电图异常以及无异常情况有关。我们报告一例健康男性在使用丙泊酚麻醉后出现非惊厥性癫痫发作和脑电图广泛性阵发性快活动的病例。
