Theiler R, Hanck A, Schreiber A, Von Hochstetter A R, Wagenhaeuser F J, Michel B A
Department of Rheumatology and Pathology, University Hospital, Basel, Switzerland.
Clin Rheumatol. 1994 Jun;13(2):293-8. doi: 10.1007/BF02249030.
A 59-year-old patient suffering from hyperlipidaemia developed a chronic vitamin A intoxication syndrome after ingestion of 30000 IE retinol/daily over a period of six years. Functional disability of the right hip was caused by radiologically documented hyperostosis of the acetabular circumference. Finally, a prosthesis had to be implanted because of rapid destructive osteoarthritis of the right hip. Implications of vitamin A for rheumatological management are discussed.
一名59岁的高脂血症患者在六年时间里每天摄入30000国际单位视黄醇后，出现了慢性维生素A中毒综合征。髋臼周围骨质增生经放射学记录证实，导致右髋关节功能障碍。最终，由于右髋关节迅速发展为破坏性骨关节炎，不得不植入假体。本文讨论了维生素A在风湿病治疗中的影响。
