Flores H, Ramalho R A, Ribeiro A R
Departamento de Nutrição, Universidade Federal de Pernambuco Cidade Universitária, Recife, Brasil.
Int J Vitam Nutr Res. 1988;58(3):276-80.
Liver vitamin A was determined in 10 different regions of the liver from 13 rats and 17 human individuals deceased of various causes. Linear regression analysis and comparison of the values obtained from the different anatomical regions showed that, despite a high degree of heterogeneity in distribution and lack of a consistent pattern, samples from any of the sites analyzed ensure representativeness of the whole liver concentration, taken as the average of the values from the 10 samples of each liver. This means that properly trained personnel, but not necessarily specialized, could draw the liver samples, thus significantly reducing the cost of surveys of vitamin A status based on liver reserves of the vitamin determined at autopsy.
对13只大鼠和17名因各种原因死亡的人类个体肝脏的10个不同区域进行了肝脏维生素A测定。线性回归分析以及对不同解剖区域所得值的比较表明，尽管分布存在高度异质性且缺乏一致模式，但所分析的任何一个部位的样本都能确保作为每个肝脏10个样本值的平均值的全肝浓度具有代表性。这意味着经过适当培训的人员（不一定是专业人员）可以采集肝脏样本，从而显著降低基于尸检时测定的维生素肝脏储备来调查维生素A状态的成本。
