[利用病毒粒子沉淀反应检测哺乳动物D型（梅森 - 辉瑞）和C型病毒粒子包膜中的共同抗原决定簇]
[Detection of common antigenic determinants in the envelopes of mammalian type D (Mason--Pfizer) and type C virions by using the virion precipitation reaction].
作者信息
Al'tshteĭn A D, Zakharova L G, Zhdanov V M
出版信息
Vopr Virusol. 1978 May-Jun(3):309-14.
Immune sera to Mason-Pfizer virus (M-PMV) are capable of precipitating type C viruses of mice (NIH-MuLV, G-MuLV, and to a lower degree R-MuLV), cats (FeLV, RD-114), and monkeys (SSV-1, GALV, BEV). The immune sera to RD-114, BEV, SSV-1 and GALV viruses can precipitate M-PMV virions. The adsorption analysis suggests that cross-reactions between M-PMV, RD-114, NIH-MuLV, and G-MuLV viruses depend on common virus-specific antigenic determinants in the envelopes of the virions. The relationship between M-PMV and type C viruses decreases in the series RD-114--NIG-MuLV--G-MuLV. Type C viruses of mammals have common envelope antigenic determinants lacking in M-PMV. No common antigenic determinants with M-PMV have been found in the envelope of virions of bovine leukemia virus, type B virus of mice (MMTV), or type C avian virus (Pr-RSV).
抗梅森- Pfizer病毒（M-PMV）的免疫血清能够沉淀小鼠的C型病毒（NIH-MuLV、G-MuLV，对R-MuLV的沉淀程度较低）、猫的C型病毒（FeLV、RD-114）以及猴的C型病毒（SSV-1、GALV、BEV）。抗RD-114、BEV、SSV-1和GALV病毒的免疫血清能够沉淀M-PMV病毒粒子。吸附分析表明，M-PMV、RD-114、NIH-MuLV和G-MuLV病毒之间的交叉反应取决于病毒粒子包膜中共同的病毒特异性抗原决定簇。M-PMV与C型病毒之间的关系在RD-114 - NIG-MuLV - G-MuLV序列中逐渐减弱。哺乳动物的C型病毒具有M-PMV所缺乏的共同包膜抗原决定簇。在牛白血病病毒、小鼠B型病毒（MMTV）或C型禽病毒（Pr-RSV）的病毒粒子包膜中未发现与M-PMV的共同抗原决定簇。
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