Hoang-Xuan T, Laroche J M, Robin H, Ullern M, Bron A, Sabatier P, Durand J
Service d'Ophtalmologie, Hôpital Bichat, Paris.
J Fr Ophtalmol. 1994;17(4):231-7.
The authors report the cases of two patients suffering of a rare long-term complication of contact lens wearing. Both patients wore daily soft contact lens for 5 and 8 years respectively. They presented with bilateral central predescemetic avascular haze associated with mild corneal stromal edema, descemetic folds in one patient and polymegethism on endothelial specular microscopic examination. The vision impairment was severe, unilateral in one patient and bilateral in the other. More than one year after removal of the contact lenses, only one patient fully recovered her initial visual acuity. The mechanisms of the onset of this corneal pseudo-dystrophy are discussed. Hypoxia and acidosis of the cornea induced by the contact lens are most probably responsible for this complication through endothelial metabolic dysfunction.
作者报告了两例患有隐形眼镜佩戴罕见长期并发症的患者病例。两名患者分别佩戴日抛型软性隐形眼镜5年和8年。他们均出现双侧中央前弹力层下无血管性混浊，并伴有轻度角膜基质水肿，其中一名患者出现后弹力层皱折，内皮细胞镜面显微镜检查显示细胞大小不均。视力损害严重，一名患者为单侧，另一名患者为双侧。摘除隐形眼镜一年多后，只有一名患者完全恢复了初始视力。本文讨论了这种角膜假性营养不良的发病机制。隐形眼镜引起的角膜缺氧和酸中毒很可能通过内皮细胞代谢功能障碍导致了这种并发症。
