Wada K, Sega H, Ishizuka O, Yoshikawa H, Tsukada H, Arakawa M
Department of Medicine (II), Niigata University Medical School.
Kansenshogaku Zasshi. 1994 Jul;68(7):837-41. doi: 10.11150/kansenshogakuzasshi1970.68.837.
Postmortem infectious lesions were analyzed in 63 patients with bacteremia and fungemia. Bacterial infection was found in 36 patients, deep mycoses in 27 and cytomegalovirus infection in 7. Among deep mycoses patients, yeast was noticed in 17, Aspergillus in 13 and Mucor in one. Infectious lesions were not observed in 10 cases. Fifteen cases of 23 leukopenic patients were complicated with deep mycoses. Deep mycoses was noticed in 43% of bacteremia and fungemia patients, but not in candicemia patients. Fungemia due to Candida was related to blood access, however, not to deep mycoses. On the other hand, disseminated mycoses was found in 4 of 5 cases with Trichosporon beigelii fungemia. T. beigelii infection is noticeably life-threatening to the immunocompromised host.
对63例菌血症和真菌血症患者的尸检感染性病变进行了分析。36例患者发现细菌感染，27例为深部真菌病，7例为巨细胞病毒感染。在深部真菌病患者中，17例发现酵母菌，13例发现曲霉菌，1例发现毛霉菌。10例未观察到感染性病变。23例白细胞减少症患者中有15例并发深部真菌病。深部真菌病在43%的菌血症和真菌血症患者中被发现，但念珠菌血症患者中未发现。念珠菌引起的真菌血症与血管通路有关，而非与深部真菌病有关。另一方面，5例白吉利丝孢酵母真菌血症患者中有4例发现播散性真菌病。白吉利丝孢酵母感染对免疫功能低下的宿主具有明显的生命威胁。
