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玻璃体后脱离的自然病史以及作为视网膜脱离首要防线的早期处理

Natural history of posterior vitreous detachment with early management as the premier line of defense against retinal detachment.

作者信息

Byer N E

机构信息

Department of Ophthalmology, University of California School of Medicine, Los Angeles.

出版信息

Ophthalmology. 1994 Sep;101(9):1503-13; discussion 1513-4. doi: 10.1016/s0161-6420(94)31141-9.

Abstract

PURPOSE

This study was designed to elucidate various aspects of the natural history of posterior vitreous detachment (PVD), in particular the relation between symptomatology and prognosis as it relates to management of patients with the earliest symptoms of PVD.

METHODS

A prospective study of 350 consecutive patients with PVD was performed, excluding all patients referred from an ophthalmologist, those with symptoms of more than 3 months in duration, and those with a history of ocular trauma, except for cataract surgery. Aphakia was present in 21 eyes, and 50 patients were bilaterally involved.

RESULTS

Of 163 patients who had one to two floaters as their presenting symptom, with or without light flashes, a retinal tear developed in 12 (7.3%). Of 31 phakic eyes with secondary retinal tears on initial examination, 9 (29%) had one to two floaters and light flashes as the only symptoms. Of eight phakic eyes that initially, or eventually, had a retinal detachment, three (37%) had an interval of 2 1/2 to 3 weeks before visual field loss, during which they noticed only one to three visual floaters plus light flashes as their only symptoms. This early stage in which symptoms are detectable is crucial in terms of providing an opportunity for early treatment that might prevent retinal detachments.

CONCLUSIONS

The prompt and conscientious vitreoretinal examination of each patient older than 45 years of age who experiences vitreous floaters, even though limited to one or two, should be undertaken without delay. This practice, combined with expeditious treatment of any secondary retinal tears, provides the most effective known means of preventing rhegmatogenous retinal detachment, and currently it appears to be neglected. A national public educational effort should be pursued to publicize the importance of these symptoms.

摘要

目的

本研究旨在阐明玻璃体后脱离(PVD)自然史的各个方面,尤其是症状学与预后之间的关系,因为这与有PVD最早症状患者的管理相关。

方法

对连续350例PVD患者进行了一项前瞻性研究,排除了所有眼科医生转诊的患者、病程超过3个月的患者以及有眼外伤史(白内障手术除外)的患者。21只眼存在无晶状体状态,50例患者为双眼受累。

结果

在163例以一至两个飞蚊症为首发症状(有或无闪光感)的患者中,12例(7.3%)发生了视网膜裂孔。在初次检查时有继发性视网膜裂孔的31只晶状体眼患者中,9例(29%)仅以一至两个飞蚊症和闪光感为唯一症状。在最初或最终发生视网膜脱离的8只晶状体眼中,3例(37%)在视野丧失前有2.5至3周的间隔期,在此期间他们仅注意到一至三个视觉飞蚊症加闪光感作为唯一症状。就提供可能预防视网膜脱离的早期治疗机会而言,症状可被检测到的这个早期阶段至关重要。

结论

对于每一位45岁以上出现玻璃体飞蚊症(即使仅限于一两个)的患者,应立即进行及时、认真的玻璃体视网膜检查。这种做法,再加上对任何继发性视网膜裂孔的迅速治疗,是预防孔源性视网膜脱离最有效的已知方法,而目前这一点似乎被忽视了。应开展全国性的公众教育活动,宣传这些症状的重要性。

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