Maguen E, Salz J J, Nesburn A B, Warren C, Macy J I, Papaioannou T, Hofbauer J, Berlin M S
Ophthalmology Research and Laser Research Laboratories, Cedars-Sinai Medical Center, Los Angeles, CA 90048.
Ophthalmology. 1994 Sep;101(9):1548-56; discussion 1556-7. doi: 10.1016/s0161-6420(94)31137-7.
This report summarizes the authors' 3-year experience with excimer laser photorefractive keratectomy on 240 eyes of 161 patients.
With constant laser emission parameters, nitrogen flow across the cornea was used on 79 eyes, whereas 161 eyes had no nitrogen flow. Of the 240 eyes, 74 were operated on without suction ring fixation. Postoperative pain management included patching and oral analgesics in 77 eyes and the use of topical diclofenac or ketorolac and a therapeutic soft contact lens in 163 eyes. Follow-up ranged from 1 month (206 eyes) to 36 months (10 eyes).
At 3 months, 88% (144 eyes) had uncorrected visual acuity of 20/40 or better; 86% (151 eyes) had corrected visual acuity to within +/- 1 diopter of intended correction, and 10% (17 eyes) lost two or more lines of best-corrected visual acuity. At 12 months, 89% (122 eyes) achieved uncorrected visual acuity of 20/40 or better, 79% (115 eyes) had corrected visual acuity to within +/- 1 diopter of intended correction, and 4% (6 eyes) lost two or more lines of best-corrected visual acuity. At 24 months, 92% (44 of 48 eyes) had uncorrected visual acuity of 20/40 or better, 86% (44 of 51 eyes) had corrected visual acuity to within +/- 1 diopter of intended correction, and 5% (2 eyes) lost two or more lines of best-corrected visual acuity. At 36 months, 90% (9 eyes) achieved an uncorrected visual acuity of 20/40 or better, 90% (9 eyes) had corrected visual acuity to within +/- 1 diopter of intended correction, and no eyes lost two or more lines of best-corrected visual acuity.
The results obtained with one procedure are within accepted standards of accuracy for refractive surgery, and there is the potential for refinement of the final optical correction. Complication rates are low and are not vision threatening. They included increased intraocular pressure, epithelial "map dot" changes, and recurrent corneal erosion syndrome, "central islands," and others. Photorefractive keratectomy appears to be a safe procedure over the short and medium term.
本报告总结了作者对161例患者的240只眼进行准分子激光屈光性角膜切削术的3年经验。
在激光发射参数恒定的情况下,79只眼在角膜上使用了氮气流动,而161只眼未使用氮气流动。在这240只眼中,74只眼手术时未使用吸引环固定。术后疼痛管理方面,77只眼采用了眼罩和口服镇痛药,163只眼使用了局部双氯芬酸或酮咯酸以及治疗性软性接触镜。随访时间从1个月(206只眼)到36个月(10只眼)不等。
3个月时,88%(144只眼)的裸眼视力达到20/40或更好;86%(151只眼)的矫正视力在预期矫正度数的±1屈光度范围内,10%(17只眼)的最佳矫正视力下降了两行或更多行。12个月时,89%(122只眼)的裸眼视力达到20/40或更好,79%(115只眼)的矫正视力在预期矫正度数的±1屈光度范围内,4%(6只眼)的最佳矫正视力下降了两行或更多行。24个月时,92%(48只眼中的44只)的裸眼视力达到20/40或更好,86%(51只眼中的44只)的矫正视力在预期矫正度数的±1屈光度范围内,5%(2只眼)的最佳矫正视力下降了两行或更多行。36个月时,90%(9只眼)的裸眼视力达到20/40或更好,90%(9只眼)的矫正视力在预期矫正度数的±1屈光度范围内,没有眼的最佳矫正视力下降两行或更多行。
该手术获得的结果在屈光手术公认的准确性标准范围内,并且最终光学矫正有进一步优化的潜力。并发症发生率低,不威胁视力。并发症包括眼压升高、上皮“地图样点状”改变、复发性角膜糜烂综合征、“中央岛”等。准分子激光屈光性角膜切削术在短期和中期似乎是一种安全的手术。