Salz J J, Maguen E, Nesburn A B, Warren C, Macy J I, Hofbauer J D, Papaioannou T, Berlin M
Department of Ophthalmology, USC School of Medicine, Los Angeles.
Ophthalmology. 1993 Jun;100(6):873-82. doi: 10.1016/s0161-6420(93)31560-5.
This report summarizes the authors' 2-year experience with excimer laser photorefractive keratectomy (PRK) on 160 eyes of 128 patients.
All eyes were treated with an excimer laser: fluence, 160 mJ/cm2; frequency, 5 Hz; ablation zone diameter, 5.0 to 5.5 mm; and depth per pulse, 0.21 to 0.27 microns. A suction fixation ring was used in all eyes either with nitrogen flow (79 eyes) or without nitrogen flow (81 eyes) across the cornea. Follow-up ranged from 1 month (152 eyes) to 24 months (12 eyes).
At 3 months, 82% (139) of eyes achieved an uncorrected visual acuity of 20/40 or better; 83% were corrected to within +/- 1 diopter (D) of intended correction and 30% lost one line of best-corrected visual acuity. At 6 months, 88% (124) of eyes achieved an uncorrected visual acuity of 20/40 or better; 84% were corrected to within +/- 1 D of intended correction and 15% lost one line of best-corrected visual acuity. At 12 months, 91% (71) of eyes achieved an uncorrected visual acuity of 20/40 or better; 84% were corrected to within +/- 1 D of intended correction and 17% lost one line of best-corrected visual acuity. At 24 months, 100% (12) of eyes achieved an uncorrected visual acuity of 20/40 or better; 91.6% were within +/- 1 D of intended correction and 0% lost one line of best-corrected visual acuity.
In eyes with a follow-up of 6 to 24 months, 77% to 100% achieved an uncorrected visual acuity of 20/40 or better and 84% to 92% were corrected to within +/- 1 D of the intended correction. The authors conclude that excimer laser PRK appears to be a safe procedure capable of correcting the eyes of patients with low to moderate myopia with approximately the same degree of accuracy as radial keratotomy.
本报告总结了作者对128例患者的160只眼进行准分子激光屈光性角膜切削术(PRK)的2年经验。
所有眼睛均接受准分子激光治疗:能量密度为160 mJ/cm²;频率为5 Hz;消融区直径为5.0至5.5 mm;每脉冲深度为0.21至0.27微米。所有眼睛均使用了吸引固定环,其中79只眼在角膜上有氮气流过,81只眼没有氮气流过。随访时间从1个月(152只眼)至24个月(12只眼)不等。
3个月时,82%(139只)眼的裸眼视力达到20/40或更好;83%的眼矫正至预期矫正度数的±1屈光度(D)以内,30%的眼最佳矫正视力下降一行。6个月时,88%(124只)眼的裸眼视力达到20/40或更好;84%的眼矫正至预期矫正度数的±1 D以内,15%的眼最佳矫正视力下降一行。12个月时,91%(71只)眼的裸眼视力达到20/40或更好;84%的眼矫正至预期矫正度数的±1 D以内,17%的眼最佳矫正视力下降一行。24个月时,100%(12只)眼的裸眼视力达到20/40或更好;91.6%的眼在预期矫正度数的±1 D以内,0%的眼最佳矫正视力下降一行。
在随访6至24个月的眼中,77%至100%的眼裸眼视力达到20/40或更好,84%至92%的眼矫正至预期矫正度数的±1 D以内。作者得出结论,准分子激光PRK似乎是一种安全的手术方法,能够以与放射状角膜切开术大致相同的准确度矫正中低度近视患者的眼睛。