Curtale F, Vaidya Y, Tilden R L
International Course for PHC Managers, Istituto Superiore di Sanità, Ministry of Health, Rome, Italy.
Panminerva Med. 1994 Mar;36(1):19-21.
The study reports on the association between serum retinol levels and prevalence of two intestinal helminths in a random sample of 592 children, 6-120 months of age. Faecal analyses were performed by Kato thick-smear technique, recording the presence of hookworm and Ascaris lumbricoides eggs. Serum retinol levels were determined by high pressure liquid chromatography (HPLC) and expressed in micrograms/dl. The presence of Ascaris lumbricoides eggs was associated with lower levels of serum retinol in children below 60 months of age (p < 0.05). The presence of hookworm eggs was not associated with lower levels of serum retinol in any age group. In addition children who received at least one course of mebendazole during the past 12 months recorded higher serum retinol levels than children who did not receive it (p < 0.01).
该研究报告了在592名年龄在6至120个月的儿童随机样本中血清视黄醇水平与两种肠道蠕虫患病率之间的关联。采用加藤厚涂片技术进行粪便分析，记录钩虫和蛔虫卵的存在情况。血清视黄醇水平通过高压液相色谱法（HPLC）测定，并以微克/分升表示。蛔虫卵的存在与60个月以下儿童血清视黄醇水平较低有关（p<0.05）。在任何年龄组中，钩虫卵的存在与血清视黄醇水平较低均无关联。此外，在过去12个月内接受过至少一个疗程甲苯达唑治疗的儿童，其血清视黄醇水平高于未接受该治疗的儿童（p<0.01）。
