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[妇科腹部手术对垂体 - 甲状腺轴功能的影响]

[Effect of gynecologic abdominal surgery on function of the hypophyseal-thyroid axis].

作者信息

Kniazewski B, Olejek A, Rzempołuch J

机构信息

I Katedry i Kliniki Połoznictwa i Ginekologii Sl. AM, Bytomiu.

出版信息

Pol Tyg Lek. 1993;48(27-28):590-4.

PMID:8090648
Abstract

Triiodothyronine (T3), free triiodothyronine (fT3), thyroxine (T4), free thyroxine, and TSH levels have been assayed in female patients undergoing gynecological surgeries of various extension (Wertheim-Meigs operation, pan-hysterectomy, unilateral adnexectomy, diagnostic laparoscopy). Laparoscopy did not produce any significant changes in the concentrations of assayed hormones. The remaining operations produced a decrease in T3 and fT3 levels and significant increase in T4 and fT4. TSH concentration also increased but this process was biphasic--an early decrease to baseline values follow by an increase. The assay of hypophyseal and thyroid hormones may serve as an indicator of the degree of the homeostasis disorders after surgical operations.

摘要

已对接受各种范围妇科手术(韦特海姆 - 梅格斯手术、全子宫切除术、单侧附件切除术、诊断性腹腔镜检查)的女性患者测定了三碘甲状腺原氨酸(T3)、游离三碘甲状腺原氨酸(fT3)、甲状腺素(T4)、游离甲状腺素和促甲状腺激素(TSH)水平。腹腔镜检查未使所测激素浓度发生任何显著变化。其余手术导致T3和fT3水平降低,T4和fT4显著升高。TSH浓度也升高,但该过程呈双相性——先是早期降至基线值,随后升高。垂体和甲状腺激素的测定可作为手术后体内稳态紊乱程度的指标。

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