Das P, Shukla H S
Br J Surg. 1975 Aug;62(8):610-7. doi: 10.1002/bjs.1800620807.
Material obtained from 35 cases of abdominal tuberculosis waps studied and an attempt was made to demonstrate tubercle bacilli by special staining of histological sections, culture and guinea-pig inoculation. Acid fast bacilli could be demonstrated in 80 per cent of cases. The remaining cases were also possibly due to tuberculous infection because granulomas with Langhans's type of giant cells and caseation or calcification of lymph nodes were present. The bacilli were demonstrated in bowel tissue showing non-specific histology in 1 case. In 2 other cases with non-specific lesions in the bowel the bacilli were demonstrated in lymph nodes. Guinea-pig inoculation studies showed that hypertrophic lesions of the bowel with a non-specific type of reaction could develop after intraperitoneal injection of tubercular material. Although it cannot be said on the basis of this study that Crohn's disease is caused by tuberculous infection, it can be concluded that tuberculous infection can give rise to a Crohn's type of lesion.
对35例腹部结核患者的材料进行了研究，并尝试通过组织学切片的特殊染色、培养和豚鼠接种来证明结核杆菌。80%的病例中可发现抗酸杆菌。其余病例也可能是结核感染所致，因为存在伴有朗汉斯巨细胞的肉芽肿以及淋巴结的干酪样坏死或钙化。在1例肠道组织显示非特异性组织学的病例中发现了杆菌。在另外2例肠道有非特异性病变的病例中，在淋巴结中发现了杆菌。豚鼠接种研究表明，腹腔注射结核材料后，肠道可出现具有非特异性反应类型的肥厚性病变。虽然根据这项研究不能说克罗恩病是由结核感染引起的，但可以得出结论，结核感染可导致克罗恩样病变。
