Atlas S W
Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia 19104.
Radiology. 1994 Oct;193(1):1-16. doi: 10.1148/radiology.193.1.8090876.
Magnetic resonance (MR) angiography has rapidly evolved over the past few years to become a technique that is commonly used in clinical practice as part of the diagnostic work-up of patients with suspected neurologic disease. In this review, the author provides a brief overview of the relevant biophysical principles and some fundamentals of flow imaging by using MR as a baseline for understanding and implementing MR angiography in these patients. A historical perspective is given as a way of emphasizing the need for a healthy degree of skepticism rather than enthusiasm alone when reading MR angiographic literature. The rationale and clinical needs for MR angiography are summarized. The available data from blinded reader studies are summarized for two major clinical entities in which MR angiography is often used in neurologic practice: atherosclerotic disease of the extracranial carotid bifurcation and intracranial aneurysms. Recent refinements and technical innovations are also noted.
在过去几年中，磁共振（MR）血管造影术迅速发展，已成为临床实践中常用于对疑似神经系统疾病患者进行诊断检查的一项技术。在本综述中，作者简要概述了相关生物物理原理以及一些利用磁共振进行血流成像的基本原理，以此作为理解和对这些患者实施MR血管造影术的基础。文中给出了一个历史视角，旨在强调在阅读MR血管造影文献时，需要保持适度的怀疑态度而非仅仅满怀热情。总结了MR血管造影术的基本原理和临床需求。还总结了针对神经科实践中经常使用MR血管造影术的两个主要临床实体——颅外颈动脉分叉处动脉粥样硬化疾病和颅内动脉瘤——的盲法阅片研究的现有数据。同时也提到了近期的改进和技术创新。
