Anderson C M, Lee R E, Levin D L, de la Torre Alonso S, Saloner D
Section of Radiology (114D), Veteran Affairs Medical Center, San Francisco, CA 94121.
Radiology. 1994 Oct;193(1):219-26. doi: 10.1148/radiology.193.1.8090894.
To determine whether interpretation of internal carotid artery (ICA) stenosis from source partitions is more accurate than interpretation from maximum-intensity projections (MIPs) from three-dimensional (3D) time-of-flight (TOF) magnetic resonance (MR) angiography.
The percentage of diameter ICA stenosis was measured on source images and MIPs from sagittal (n = 150) and transverse (n = 140) 3D TOF MR angiography. Measurements were compared with those from conventional angiography.
Sensitivity and specificity for distinguishing 70%-99% stenosis were 96% and 78%, respectively, for sagittal MIPs, 88% and 90% for sagittal source images, 92% and 86% for transverse MIPs, and 92% and 95% for transverse source images. Areas under the receiver operating characteristic curves statistically significantly increased (P < .05) with interpretation from source images. Complete loss of intravascular signal was not encountered on source partitions except within a greater than 85% stenosis.
Interpretation of source partitions rather than MIPs reduces the tendency for overestimation of stenosis with MR angiography and improves the specificity for discriminating 70%-99% stenosis.
确定从源图像分区解读颈内动脉（ICA）狭窄是否比从三维（3D）时间飞跃（TOF）磁共振（MR）血管造影的最大强度投影（MIP）解读更准确。
在矢状位（n = 150）和横断位（n = 140）3D TOF MR血管造影的源图像和MIP上测量ICA直径狭窄百分比。将测量结果与传统血管造影的结果进行比较。
区分70%-99%狭窄的敏感度和特异度，矢状位MIP分别为96%和78%，矢状位源图像为88%和9%，横断位MIP为92%和86%，横断位源图像为92%和95%。随着从源图像进行解读，受试者操作特征曲线下面积有统计学显著增加（P <.05）。除了在大于85%的狭窄内，在源图像分区上未遇到血管内信号完全消失的情况。
解读源图像分区而非MIP可减少MR血管造影对狭窄高估的倾向，并提高区分70%-99%狭窄的特异度。
