Yamashita Y, Hatanaka Y, Yamamoto H, Arakawa A, Matsukawa T, Miyazaki T, Takahashi M
Department of Radiology, Kumamoto University School of Medicine, Japan.
Radiology. 1994 Oct;193(1):59-65. doi: 10.1148/radiology.193.1.8090922.
To evaluate the role of spin-echo (SE) and contrast material-enhanced dynamic magnetic resonance (MR) imaging in the differential diagnosis of focal liver lesions.
Conventional T1- and T2-weighted SE and fast low-angle shot dynamic MR imaging were performed in 300 focal liver lesions on a 1.5-T MR imager. Findings at both SE and dynamic imaging were analyzed by means of univariate and multivariate analysis.
Although considerable overlap existed, signal intensity on T2-weighted images, tumor margin, and internal architecture were significant factors for SE imaging. For dynamic imaging, the hemodynamics and pattern of enhancement were significant factors. A logistic regression analysis revealed 86% of lesions were correctly categorized with these parameters.
A specific diagnosis of liver lesions can be obtained in most cases by combining parameters obtained from SE and dynamic MR images.
评估自旋回波（SE）和对比剂增强动态磁共振（MR）成像在肝脏局灶性病变鉴别诊断中的作用。
在一台1.5-T MR成像仪上，对300例肝脏局灶性病变进行常规T1加权和T2加权SE及快速低角度激发动态MR成像。通过单变量和多变量分析对SE和动态成像的结果进行分析。
尽管存在相当大的重叠，但T2加权图像上的信号强度、肿瘤边缘和内部结构是SE成像的重要因素。对于动态成像，血流动力学和强化模式是重要因素。逻辑回归分析显示，利用这些参数可正确分类86%的病变。
通过结合从SE和动态MR图像获得的参数，大多数情况下可对肝脏病变做出明确诊断。
