Soyer P, Bluemke D A, Hruban R H, Sitzmann J V, Fishman E K
Department of Radiology, Johns Hopkins Hospital, Baltimore, Md.
Radiology. 1994 Oct;193(1):71-4. doi: 10.1148/radiology.193.1.8090923.
To determine the sensitivity and false-positive rate of helical computed tomography during arterial portography (CTAP) in the detection of hepatic metastases from colorectal cancer.
Preoperative helical CTAP was performed to examine 23 patients (10 men and 13 women, aged 43-77 years [mean, 63 years]) who later underwent surgical tumor resection. Imaging findings were retrospectively reviewed by two radiologists and were correlated with intraoperative and histologic findings.
Helical CTAP demonstrated 33 of 35 metastases, with diameters of 4-95 mm, that were identified in resected specimens (sensitivity, 94%). The two metastases not demonstrated were 4 and 5 mm in diameter. Five false-positive lesions were found in four patients, yielding a false-positive rate of 17% by patient analysis and 13% by lesion analysis.
The sensitivity of helical CTAP in the preoperative detection of hepatic metastases is high, and its false-positive rate compares favorably with that of conventional CTAP, but future comparative studies are needed to determine which is the better modality.
确定螺旋计算机断层扫描在动脉门静脉造影（CTAP）期间检测结直肠癌肝转移灶的敏感性和假阳性率。
对23例患者（10例男性，13例女性，年龄43 - 77岁[平均63岁]）进行术前螺旋CTAP检查，这些患者随后接受了肿瘤手术切除。两名放射科医生对影像结果进行了回顾性分析，并与术中及组织学结果进行了对照。
螺旋CTAP显示在切除标本中发现的35个转移灶中的33个，直径为4 - 95毫米（敏感性为94%）。未显示的两个转移灶直径分别为4毫米和5毫米。在4例患者中发现了5个假阳性病变，通过患者分析假阳性率为17%，通过病变分析为13%。
螺旋CTAP在术前检测肝转移灶方面敏感性较高，其假阳性率与传统CTAP相比具有优势，但未来需要进行对比研究以确定哪种方法更好。
