Braun U, Götz M, Guscetti F
Clinic of Veterinary Internal Medicine, University of Zurich, Switzerland.
Schweiz Arch Tierheilkd. 1994;136(8):275-9.
This case report describes a 6-year-old Holstein Friesian cow with extrahepatic cholestasis. The most prominent clinical signs were disturbed general condition and behaviour, icterus, yellowish brown urine, and bilirubinuria. An increased concentration of serum bilirubin and an increase in hepatic enzyme activity were the most important laboratory findings. Ultrasonographic examination of the liver and gall bladder revealed severe bile stasis. The intrahepatic bile ducts, the cystic duct, and the gall bladder were severely dilated. Histological examination of a liver biopsy revealed cholestasis, cholangitis, and acute hepatosis. A liver abscess was also found at post mortem examination. It was assumed that cholestasis was caused by the inflammatory products resulting from cholangitis.
本病例报告描述了一头患有肝外胆汁淤积的6岁荷斯坦奶牛。最突出的临床症状是全身状况和行为紊乱、黄疸、黄褐色尿液和胆红素尿。血清胆红素浓度升高和肝酶活性增加是最重要的实验室检查结果。肝脏和胆囊的超声检查显示严重胆汁淤积。肝内胆管、胆囊管和胆囊严重扩张。肝脏活检的组织学检查显示胆汁淤积、胆管炎和急性肝病。死后检查还发现一个肝脓肿。推测胆汁淤积是由胆管炎产生的炎性产物引起的。
