Barabino Arrigo Vittorio, Castellano Emanuela, Gandullia Paolo, Torrente Franco, Guida Alessandra, Magnano Gian Michele
Paediatric Gastroenterology Unit, G. Gaslini Institute, L.go G. Gaslini 5, 16148 Genoa, Italy.
Eur J Pediatr. 2003 Oct;162(10):666-8. doi: 10.1007/s00431-003-1279-7. Epub 2003 Aug 12.
A case of chronic eosinophilic ascites with onset in early infancy is described. An intensive diagnostic work-up ruled out other known causes of ascites in childhood. The final diagnosis was made at 2 years of age when a large number of eosinophils was detected in the ascitic fluid. The outcome was complicated by an ex vacuo intraperitoneal haemorrhage. Steroids were able to control the disease only after complete aspiration (1600 ml) of the ascitic fluid. On discontinuation of treatment, peritoneal inflammation recurred indicating steroid-dependency.
eosinophilic ascites, a very rare disorder in children, should be considered in the differential diagnosis of even very young children presenting with ascites.
本文描述了一例婴儿早期发病的慢性嗜酸性粒细胞性腹水病例。全面的诊断性检查排除了儿童腹水的其他已知病因。最终诊断在患儿2岁时做出,当时在腹水中检测到大量嗜酸性粒细胞。结果因腹腔内相对性出血而复杂化。仅在完全抽出(1600毫升)腹水后,类固醇药物才能够控制病情。治疗中断后,腹膜炎复发,提示类固醇依赖。
嗜酸性粒细胞性腹水在儿童中非常罕见,对于出现腹水的幼儿,即使是年龄很小的幼儿,在鉴别诊断中也应考虑到该病。