Knowles B A, Cooley L
Department of Genetics, Yale University School of Medicine, New Haven, CT 06510.
Trends Genet. 1994 Jul;10(7):235-41. doi: 10.1016/0168-9525(94)90170-8.
The Drosophila egg chamber is emerging as a uniquely versatile system for studying cytoskeletal rearrangements during development. Initial determination of the oocyte fate and subsequent growth of the oocyte depend on a series of highly coordinated changes in cell architecture. Homologs or relatives of many known cytoskeletal proteins play key roles in these events.
果蝇卵室正逐渐成为研究发育过程中细胞骨架重排的一个极具通用性的独特系统。卵母细胞命运的初始决定以及随后卵母细胞的生长取决于细胞结构中一系列高度协调的变化。许多已知细胞骨架蛋白的同源物或相关蛋白在这些事件中发挥着关键作用。