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[高脂血症与肿瘤:携带恶性淋巴瘤仓鼠的肝素后脂肪酶活性]

[Hyperlipemia and tumors : post heparin lipase activity of the hamster bearing a malignant lymphoma].

作者信息

Beaumont V, Bérard M, Boisnier C, Beaumont J L

出版信息

C R Acad Hebd Seances Acad Sci D. 1975 Feb 3;280(5):665-8.

PMID:809163
Abstract

Subcutaneous transplantation of Greene lymphoma in golden hamsters is followed by a type IV-V hyperlipoproteinemia with major hupertriglyceridemia and impairment of labelled triglyceride clearance. Postheparin lipase activity studies show that this hyperlipidemia is correlated with the decrease in the lipolytic enzyme, which plays an important role in triglyceride clearance. The role of the tumor is considered.

摘要

将格林淋巴瘤皮下移植到金黄仓鼠体内后,会出现IV - V型高脂蛋白血症,伴有严重的高甘油三酯血症以及标记甘油三酯清除受损。肝素后脂肪酶活性研究表明,这种高脂血症与脂解酶的减少相关,而脂解酶在甘油三酯清除中起重要作用。文中对肿瘤的作用进行了探讨。

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