[仓鼠中伴有高甘油三酯血症的恶性淋巴瘤的抗肝素免疫球蛋白]

[Antiheparin immunoglobulin in malignant lymphoma with hypertriglyceridemia, in the hamster].

作者信息

Beaumont J L, Beaumont V, Boisnier C, Szondy E, Vranckx R

出版信息

C R Acad Hebd Seances Acad Sci D. 1976 Nov 8;283(11 D):1369-72.

Abstract

A massive hypertriglyceridemia associated with low post heparin lipolytic activity, was demonstrated during the growth of a transplanted lymphoma in Hamsters. An immunoglobulin, with high anti-heparin activity, was extracted from the tumor. It could inhibit both the anti-thrombin and prolipase activity of heparin. The role of this anti-heparin immunoglobulin in triglyceride metabolism allows us to consider the hypertriglyceridemia of lymphoma-bearing Hamsters as one of the two previously described types of auto-immune hyperlipidemia.

摘要

在仓鼠移植性淋巴瘤生长过程中，出现了与肝素后脂解活性降低相关的严重高甘油三酯血症。从肿瘤中提取出一种具有高抗肝素活性的免疫球蛋白。它能抑制肝素的抗凝血酶和前脂肪酶活性。这种抗肝素免疫球蛋白在甘油三酯代谢中的作用，使我们能够将荷瘤仓鼠的高甘油三酯血症视为先前描述的两种自身免疫性高脂血症类型之一。

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[Antiheparin immunoglobulin in malignant lymphoma with hypertriglyceridemia, in the hamster].[仓鼠中伴有高甘油三酯血症的恶性淋巴瘤的抗肝素免疫球蛋白]

C R Acad Hebd Seances Acad Sci D. 1976 Nov 8;283(11 D):1369-72.

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