Gapochko K G, Misnikov O P, Kolkov V F, Kekcheeva N G, Semenova B N, Titova T S
Voen Med Zh. 1994 Apr(4):42-6, 79.
The article substantiates epidemiological expediency of complex (associated) immunization of servicemen and population against typhoid, typhus and plague in polyetiological zones of these infections, and also in cases of simultaneous proliferation of these diseases. For simultaneous preventive vaccination against these infections a complex immunization scheme was experimentally substantiated and clinically approved. It is based on national commercial vaccines and ensures a simultaneous administration of 2-3 vaccine preparations by hypodermic syringe or jet injection. Typhoid and typhus vaccines are injected under one shoulder-blade, and plague vaccine is injected under another shoulder-blade. This complex vaccine is harmless, moderately reactogenic, develops expressing immunity which have the same protective features as monovaccines alone. This scheme is recommended for use in anti-epidemic practice.
该文章证实了在这些感染的多病因区域以及这些疾病同时流行的情况下，对军人和民众进行伤寒、斑疹伤寒和鼠疫联合（相关）免疫的流行病学合理性。对于针对这些感染的同时预防性接种，一种联合免疫方案已通过实验证实并获得临床认可。它基于国产商业疫苗，可通过皮下注射器或喷射注射同时接种两种至三种疫苗制剂。伤寒和斑疹伤寒疫苗在一侧肩胛骨下方注射，鼠疫疫苗在另一侧肩胛骨下方注射。这种联合疫苗无害，反应原性适中，能产生具有与单一疫苗相同保护特性的显著免疫力。该方案推荐用于防疫实践。
