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[几株对黄曲霉毒素B1敏感和抗性的苏云金芽孢杆菌(Berliner)菌株的霉菌毒素敏感性]

[The mycotoxin sensitivity of several Bacillus thuringiensis (Berliner) strains sensitive and resistant to aflatoxin B1].

作者信息

Boutibonnes P

出版信息

C R Acad Hebd Seances Acad Sci D. 1975 Feb 24;280(8):1031-4.

PMID:809186
Abstract

Antimicrobial activity of pure preparations of seven mycotoxins, coumarin and dicoumarin, was studied against various strains of Bacillus thuringiensis (Berliner). The acquisition of resistance to Aflatoxin B1, by a new strain designated "stable variant", obtained in the presence of mycotoxin lethal dose, is very specific. However, a relation seems to exist between Aflatoxin B1 susceptibility and sensitivity to compounds which possess a double furan ring. In vitro, coumarin exhibits an inhibitory effect against antibacterial activity of Aflatoxin B1.

摘要

研究了七种霉菌毒素纯制剂、香豆素和双香豆素对苏云金芽孢杆菌(Berliner)不同菌株的抗菌活性。在霉菌毒素致死剂量存在的情况下获得的一种新菌株“稳定变体”对黄曲霉毒素B1产生抗性的情况非常特殊。然而,黄曲霉毒素B1敏感性与对具有双呋喃环的化合物的敏感性之间似乎存在关联。在体外,香豆素对黄曲霉毒素B1的抗菌活性表现出抑制作用。

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