Jasek A M, Day H J
Department of Medicine, Abington Memorial Hospital, Pennsylvania.
Am J Hematol. 1994 Oct;47(2):129-31. doi: 10.1002/ajh.2830470212.
An 83-year-old woman with no previous history of malignancy was admitted to our institution with weakness and anemia and subsequently developed acute tumor lysis syndrome secondary to newly diagnosed Burkitt's leukemia/lymphoma. This syndrome has been previously described in patients with hematologic malignancies; however, its development has been related to the administration of chemotherapy, steroids, or radiotherapy. The spontaneous occurrence of tumor lysis syndrome has not been previously reported; however, Cohen et al. [Am J Med 58:486-491, 1980] report 8 of 37 patients with "clinically insignificant pretreatment derangements" of serum potassium, phosphate, and calcium.
一名83岁、既往无恶性肿瘤病史的女性因虚弱和贫血入住我院，随后因新诊断的伯基特白血病/淋巴瘤继发急性肿瘤溶解综合征。该综合征此前已在血液系统恶性肿瘤患者中有所描述；然而，其发生与化疗、类固醇或放疗的应用有关。此前尚未报道过肿瘤溶解综合征的自发发生；不过，科恩等人[《美国医学杂志》58:486 - 491，1980年]报告称，37例血清钾、磷酸盐和钙“预处理时临床意义不大的紊乱”患者中有8例出现这种情况。
