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幽门螺杆菌侵入胃黏膜固有层的可能性

[Possibility of Helicobacter pylori invasion into the lamina propria of the gastric mucosa].

作者信息

Morozov I A

出版信息

Arkh Patol. 1994 May-Jun;56(3):19-22.

PMID:8092933
Abstract

Biopsies of the stomach antrum and fundus from 20 male patients with non-ulcer dyspepsia were studied light- and electron-microscopically. Helicobacter pylori infection was found in 60% of cases. In 2 patients, the bacteria were found not only in the fovea and mucus, but in the tunica propria as well. The bacteria were observed in the dilated intercellular spaces of the epithelium, between epithelium and basal membrane as well as around the glands and capillaries in the form of colonies. In the tunica propria the bacteria were represented mainly by the coccus forms, they had the signs of involution. There were signs of the bacterial influence on immunocompetent cells.

摘要

对20例非溃疡性消化不良男性患者的胃窦和胃底活检组织进行了光镜和电镜研究。60%的病例中发现幽门螺杆菌感染。在2例患者中,不仅在胃小凹和黏液中发现了细菌,固有层中也有。细菌以菌落形式存在于上皮细胞扩张的细胞间隙、上皮与基底膜之间以及腺体和毛细血管周围。在固有层中,细菌主要呈球菌形态,有退化迹象。有细菌对免疫活性细胞产生影响的迹象。

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