Iwanaka T, Tamura M, Tanaka K, Komuro H, Tsuchida Y, Okai T
Department of Pediatric Surgery, Faculty of Medicine, University of Tokyo, Japan.
Asia Oceania J Obstet Gynaecol. 1994 Jun;20(2):115-20. doi: 10.1111/j.1447-0756.1994.tb00435.x.
The delay of surgery in conjunction with high-frequency oscillation ventilation combined with preoperative stabilization is a standard treatment for congenital diaphragmatic hernia neonates in the high-risk group. A new protocol of perinatal stabilization with this preoperative stabilization has been developed at the University of Tokyo Hospital. The most important components of this method of perinatal stabilization are cesarean section and the injection of morphine and pancuronium through the umbilical vein prior to ligation of the umbilical cord. In order to benefit from this treatment, congenital diaphragmatic hernia patients should be diagnosed antenatally by ultrasonography and be delivered by cesarean section. This protocol of perinatal stabilization appears effective in congenital diaphragmatic hernia patients.
对于高危组先天性膈疝新生儿,手术延迟联合高频振荡通气及术前稳定处理是标准治疗方法。东京大学医院已制定了一种采用这种术前稳定处理的围产期稳定新方案。这种围产期稳定处理方法的最重要组成部分是剖宫产以及在结扎脐带前经脐静脉注射吗啡和潘库溴铵。为了从这种治疗中获益,先天性膈疝患者应在产前通过超声检查确诊,并通过剖宫产分娩。这种围产期稳定处理方案对先天性膈疝患者似乎有效。