Goh D W, Drake D P, Brereton R J, Kiely E M, Spitz L
Department of Paediatric Surgery, Hospitals for Sick Children, London, UK.
Br J Surg. 1992 Jul;79(7):644-6. doi: 10.1002/bjs.1800790716.
Between January 1987 and December 1990, 67 neonates were treated for congenital diaphragmatic hernia, symptomatic within 6 h of birth. The mortality rate was 33 per cent. Preoperative stabilization was achieved in 47 patients, all of whom survived initial treatment, although two died later. Stabilization could not be achieved in 20 neonates, all of whom died within 3 days of birth, 18 without undergoing operation and two after early repair. Intensive resuscitation with controlled, delayed operation for congenital diaphragmatic hernia gives long-term results similar to those of urgent operative repair. This approach avoids operation in the majority of those who subsequently die.
1987年1月至1990年12月期间,67例先天性膈疝新生儿在出生后6小时内出现症状并接受治疗。死亡率为33%。47例患者实现了术前稳定,所有这些患者均在初始治疗后存活,尽管有2例后来死亡。20例新生儿未能实现稳定,所有这些患儿均在出生后3天内死亡,其中18例未接受手术,2例在早期修复后死亡。对先天性膈疝进行控制性延迟手术的强化复苏所取得的长期效果与紧急手术修复相似。这种方法可避免大多数随后死亡的患者接受手术。