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Mast cell sensitizing antibodies in myasthenia gravis.

作者信息

Schwartz J, Eyquem A, Vardinon N

出版信息

Immunol Commun. 1975;4(3):243-50. doi: 10.3109/08820137409055777.

DOI:10.3109/08820137409055777
PMID:809349
Abstract

Mast Cells Sensitizing Antibodies (MCSAb) were detected in patients with Myasthenia Gravis (MGr), by the Indirect Mast Cell Degranulation (IMCD). In most of the examined sera a correlation could be established between MCSAb and fluorescent antibodies to muscle and to thymus. The MCSAb were specific for muscle extract. They were resistant to prolonged heating and their reactivity in the IMCD test was not complement depending. Presence of MCSAb in sera of patients with MGr evidences the auto-allergic features of this disease.

摘要

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