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帕金森病管理的最新进展。

Update on the management of Parkinson's disease.

作者信息

Standaert D G, Stern M B

机构信息

Department of Neurology, University of Pennsylvania, Philadelphia.

出版信息

Med Clin North Am. 1993 Jan;77(1):169-83.

PMID:8093493
Abstract

Parkinson's disease is one of the most common neurologic disorders. Recent advances have shed new light on the nature of the disease process and have led to new strategies for management. This article reviews the biology of Parkinson's disease, the diagnostic approach to patients with parkinsonism, pharmacologic treatments, and practical strategies for managing common clinical problems.

摘要

帕金森病是最常见的神经系统疾病之一。最近的进展为该疾病进程的本质带来了新的认识,并催生了新的治疗策略。本文综述了帕金森病的生物学机制、帕金森综合征患者的诊断方法、药物治疗以及处理常见临床问题的实用策略。

相似文献

1
Update on the management of Parkinson's disease.帕金森病管理的最新进展。
Med Clin North Am. 1993 Jan;77(1):169-83.
2
Recent advances in the clinical pharmacology of Parkinson's disease.帕金森病临床药理学的最新进展。
Therapie. 1991 Jul-Aug;46(4):293-303.
3
[Therapeutic strategies in Parkinson's disease].[帕金森病的治疗策略]
Arch Neurobiol (Madr). 1991 Nov-Dec;54(6):277-81.
4
An integrated approach to patient management in Parkinson's disease.
Neurol Clin. 1992 May;10(2):553-65.
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Recent advances in Parkinson's disease therapy: use of monoamine oxidase inhibitors.帕金森病治疗的最新进展:单胺氧化酶抑制剂的应用
Expert Rev Neurother. 2005 Nov;5(6):811-21. doi: 10.1586/14737175.5.6.811.
6
[Diagnosis and therapy of Parkinson's disease].[帕金森病的诊断与治疗]
MMW Fortschr Med. 2005 May 17;147 Spec No 2:28-31.
7
Recent advances in Parkinson's disease.帕金森病的最新进展
Ideggyogy Sz. 2002 Nov 20;55(11-12):406-7.
8
Therapy of Parkinson's disease: are we at the end of the road?帕金森病的治疗:我们已走到尽头了吗?
J Assoc Physicians India. 1992 Jun;40(6):361-3.
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[Hallucinations in Parkinson's disease].[帕金森病中的幻觉]
Nervenarzt. 2003 Apr;74(4):376-85, quiz 385-6. doi: 10.1007/s00115-003-1511-8.
10
Parkinson's disease. Diagnosis and the initiation of therapy.帕金森病。诊断与治疗的启动。
Minerva Med. 2005 Jun;96(3):145-54.

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Comparative effects of acute or chronic administration of levodopa to 6-OHDA-lesioned rats on the expression and phosphorylation of N-methyl-D-aspartate receptor NR1 subunits in the striatum.左旋多巴急性或慢性给药对6-羟基多巴胺损伤大鼠纹状体中N-甲基-D-天冬氨酸受体NR1亚基表达和磷酸化的比较作用。
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3
Changes in subcellular distribution and phosphorylation of GluR1 in lesioned striatum of 6-hydroxydopamine-lesioned and l-dopa-treated rats.
6-羟基多巴胺损伤及左旋多巴治疗大鼠损伤纹状体中GluR1的亚细胞分布和磷酸化变化
Neurochem Res. 2006 Nov;31(11):1337-47. doi: 10.1007/s11064-006-9177-9. Epub 2006 Oct 20.
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Does levodopa accelerate Parkinson's disease?左旋多巴会加速帕金森病的发展吗?
Drugs Aging. 1999 Jun;14(6):399-408. doi: 10.2165/00002512-199914060-00001.
5
Salsolinol, catecholamine metabolites, and visual hallucinations in L-dopa treated patients with Parkinson's disease.左旋多巴治疗的帕金森病患者中的salsolinol、儿茶酚胺代谢产物与视幻觉
J Neural Transm (Vienna). 1996;103(4):421-32. doi: 10.1007/BF01276418.