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暴发性肝衰竭患者颅内压监测的并发症

Complications of intracranial pressure monitoring in fulminant hepatic failure.

作者信息

Blei A T, Olafsson S, Webster S, Levy R

机构信息

Department of Medicine, Northwestern University School of Medicine, Chicago, Illinois.

出版信息

Lancet. 1993 Jan 16;341(8838):157-8. doi: 10.1016/0140-6736(93)90016-a.

Abstract

In patients with fulminant hepatic failure, brain oedema and the resulting intracranial hypertension often lead to death; intracranial pressure (ICP) monitoring may therefore be valuable. However, there is uncertainty about the hazards of implanting ICP monitoring devices. We carried out a survey of complications associated with ICP monitoring among centres performing liver transplantation in the USA (n = 262 patients). Epidural transducers were the most commonly used devices and had the lowest complication rate (3.8%); subdural bolts and parenchymal monitors (fibreoptic pressure transducers in direct contact with brain parenchyma and intraventricular catheters) were associated with complication rates of 20% and 22%, respectively. Fatal haemorrhage occurred in 1% of patients undergoing epidural ICP monitoring, whereas subdural and intraparenchymal devices had fatal haemorrhage rates of 5% and 4%. Thus, in the setting of fulminant hepatic failure, epidural transducers may be the safest choice for ICP monitoring, even though they are known to be less precise than the other devices.

摘要

在暴发性肝衰竭患者中,脑水肿及由此导致的颅内高压常导致死亡;因此,颅内压(ICP)监测可能很有价值。然而,植入ICP监测设备的风险尚不确定。我们对美国进行肝移植的中心中与ICP监测相关的并发症进行了一项调查(n = 262例患者)。硬膜外传感器是最常用的设备,并发症发生率最低(3.8%);硬膜下螺栓和实质监测器(与脑实质直接接触的光纤压力传感器和脑室内导管)的并发症发生率分别为20%和22%。接受硬膜外ICP监测的患者中有1%发生致命性出血,而硬膜下和脑实质内设备的致命性出血率分别为5%和4%。因此,在暴发性肝衰竭的情况下,硬膜外传感器可能是ICP监测的最安全选择,尽管已知其不如其他设备精确。

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