Blei A T, Olafsson S, Webster S, Levy R
Department of Medicine, Northwestern University School of Medicine, Chicago, Illinois.
Lancet. 1993 Jan 16;341(8838):157-8. doi: 10.1016/0140-6736(93)90016-a.
In patients with fulminant hepatic failure, brain oedema and the resulting intracranial hypertension often lead to death; intracranial pressure (ICP) monitoring may therefore be valuable. However, there is uncertainty about the hazards of implanting ICP monitoring devices. We carried out a survey of complications associated with ICP monitoring among centres performing liver transplantation in the USA (n = 262 patients). Epidural transducers were the most commonly used devices and had the lowest complication rate (3.8%); subdural bolts and parenchymal monitors (fibreoptic pressure transducers in direct contact with brain parenchyma and intraventricular catheters) were associated with complication rates of 20% and 22%, respectively. Fatal haemorrhage occurred in 1% of patients undergoing epidural ICP monitoring, whereas subdural and intraparenchymal devices had fatal haemorrhage rates of 5% and 4%. Thus, in the setting of fulminant hepatic failure, epidural transducers may be the safest choice for ICP monitoring, even though they are known to be less precise than the other devices.
在暴发性肝衰竭患者中,脑水肿及由此导致的颅内高压常导致死亡;因此,颅内压(ICP)监测可能很有价值。然而,植入ICP监测设备的风险尚不确定。我们对美国进行肝移植的中心中与ICP监测相关的并发症进行了一项调查(n = 262例患者)。硬膜外传感器是最常用的设备,并发症发生率最低(3.8%);硬膜下螺栓和实质监测器(与脑实质直接接触的光纤压力传感器和脑室内导管)的并发症发生率分别为20%和22%。接受硬膜外ICP监测的患者中有1%发生致命性出血,而硬膜下和脑实质内设备的致命性出血率分别为5%和4%。因此,在暴发性肝衰竭的情况下,硬膜外传感器可能是ICP监测的最安全选择,尽管已知其不如其他设备精确。